Our flow cytometry data indicate that MT-6 induces G2/M phase arrest, and Western blotting experiments showed that it upregulates mitotic markers (p-histone H3, cyclin B1, and MPM2), further leading to activation of apoptotic signaling by promoting cleavage of caspases and PARP in ovarian cancer cells (Fig. 2 and Supplementary Fig. S1). This evidence concerns the gene CCNB1 and ovarian carcinoma.