NLRC5 and viral infectious disease: We show that the transcripts of Dram1, a p53-responsive regulator of autophagy27 that can be induced by viral infection,28,29Chop, an unfolded protein response-activated transcription factor involved in antiviral response30 and Nlrc5, a classical antiviral response gene,31,32 were all induced to higher levels in the presence of p19Arf+IFNβ (Figure 3g).