Plin3 is a marker protein for peripheral LDs, while Plin2 is a marker protein for larger ones.39,40 TOMM20 is a translocase of the outer mitochondrial membrane.41 Transfection of the human liver cancer cell line HepG2 revealed a co-localization of the V-domain from the murine BAX protein with TOMM20-RFP (Figure 4b) and PLIN2-RFP (Figure 4a) and only a partial co-localization with PLIN3-RFP (Supplementary Figure 1). The gene discussed is PLIN3; the disease is liver cancer.