Similar differences can be observed in the case of NER system genes studied by us—23Gly/Ala of XPA gene is suggested to have no influence on risk of colorectal cancer [31, 32], while our results indicate the opposite (odds ratio (OR) 5.373 (3.418–8.446); p < 0.0001; Table 4). This evidence concerns the gene XPA and colorectal cancer.