The beneficial effects of angiotensin-converting enzyme (ACE) inhibitors in the treatment of arterial hypertension, congestive heart failure, and other cardiovascular diseases are well documented (Hansson et al., 1999; Jorde et al., 2000; Yusuf et al., 2000; Lindholm et al., 2002; Jandeleit-Dahm et al., 2005; Feldstein, 2014; Te Riet et al., 2015). The gene discussed is ACE; the disease is cardiovascular disorder.