At 8–10 months post inoculation, all four FIV-infected cats transitioned into the asymptomatic phase of infection where plasma and peripheral blood mononuclear cell (PBMC)-associated viral gag RNA became rare to undetectable.[7] The viral transcription status in the acute and chronic phases of FIV have been intensely documented in these cats.[8–10] Three of the FIV-infected cats have been considered to be progressors, demonstrating the typical immunopathologic hallmark of FIV-infection characterized by very low numbers of peripheral CD4+ T cells. The gene discussed is CD4; the disease is infection.