Comparing the distribution of NK cell subsets at baseline between these vaccine ‘responder’ and ‘non‐responder’ groups, individuals where boosting of the HCC driven IFN‐γ response was observed after vaccination tended to have lower frequencies of CD57‐ cells at baseline, a trend also observed for children alone (Fig. 4D and E). Here, B3GAT1 is linked to hepatocellular carcinoma.