Since the gMDSCs derived from metastatic 4T1 tumour-bearing animals were able to suppress the EMT-related genes and also induce distinct set of genes; S100A9, MMP8, S100A8, WFDC21, LYZ2, FPR1, CCL3, TGFb2 (Fig. 5f; Supplementary Data 6 and 7), we reasoned whether these genes could be specific for metastatic/aggressive behaviour. The gene discussed is S100A9; the disease is neoplasm.