LPAR1 and bronchopulmonary dysplasia: However, in adult LPAR1-deficient rats with BPD the LPS-induced influx of macrophages (Figures 5H,I) and neutrophils (Figure 5J) in lung tissue sections and the level of IL-6 in lung tissue homogenates (Figure 5K) were lower compared to Wistar rats with BPD: 2.4-fold, p < 0.001 for macrophages; 2.1-fold, p < 0.05 for neutrophils; and 2.2-fold, p < 0.001 for IL-6 expression.