To determine whether miR-370 conferred to the tumor-suppressive effect of KCNQ1OT1’s inhibition, we transfected over-expression of miR-370 or miR-370 inhibitors into the stable sh-KCNQ1OT1 cells prior to the assessment of cell proliferation, apoptosis, migration and invasion. The gene discussed is KCNQ1OT1; the disease is neoplasm.