Inhibition of LIMK1 activity and HIV-mediated actin dynamics has been shown to block HIV entry, nuclear migration, viral release, and cell-cell transmission, suggesting that LIMK1 is a host dependency factor necessary for HIV infection (11, 14; L. C. Zony and B. K. Chen, presented at the 2015 Meeting on Retroviruses, Cold Spring Harbor Laboratory, 18 to 23 March 2015, Cold Spring Harbor, NY, USA). The gene discussed is LIMK1; the disease is HIV infectious disease.