We studied such cross-setting translation using a diabetes care QI intervention, the ‘ALL Initiative,’ or ‘ALL.’ At Kaiser Permanente (an integrated care system serving insured patients), ALL substantially improved rates of guideline-concordant prescribing of cardioprotective statins and angiotensin-converting enzyme inhibitor (ACEI)/angiotensin II receptor blockers (ARBs) to patients with diabetes [1]. This evidence concerns the gene ACE and diabetes mellitus.