Although the CCND1 G870A polymorphism has been investigated in a number of cancers [10–13], there are few studies on the association of the CCND1 G870A polymorphism with glioma risk and the potential correlation between the CCND1 G870A polymorphism and glioma risk is not clear yet, till now, limited population based studies have been conducted to investigate the association between CCND1 G870A polymorphism and glioma risk. The gene discussed is CCND1; the disease is central nervous system cancer.