Previous study coming from our and others have found miR-132 presented tumor-promoting but miR-212 served as tumor-suppressing feature in stomach adenocarcinoma (STAD) [27, 28], in here, the genes, i.e., SIRT1 and MECP2 with such similar reverse feature were shown to be down-regulated and up-regulated in STAD [29, 30], have conspicuously negative connection with miR-132-3p and miR-212-3p in STAD, which partially confirms the fact that both miRs have reverse functions in some tumors. This evidence concerns the gene SIRT1 and gastric adenocarcinoma.