MTOR and epilepsy: To achieve a more comprehensive analysis of target gene, the same analysis was carried on remaining predicted targets, Axon guidance ranked first in these genes, previous study have found hippocampal axon guidance can be regulated by nor-1 and involve in seizure susceptibility [44], and mTOR signaling pathway can sever as a new therapeutic strategy in epilepsy and epileptogenesis, all which absented in validated target genes may be provide a valuable reference and guide for future study on miR-212/132in epilepsy.