UCA1 and metastatic malignant neoplasm in the lymph nodes: A total of five studies explored the relationship between UCA1 and clinicopathological characteristics of colorectal cancer [16, 19, 21, 24, 27], including five studies regarding gender, differentiation grade and TNM stage, four studies of depth of primary tumor invasion and distant metastasis, three studies involving tumor size, location and lymphatic invasion, two studies of lymph node metastasis and venous invasion (Table 4).