Furthermore, to clarify the clinical relevance of T-cell markers other than CD5 in primary DLBCL, we retrospectively analyzed 169 patients with DLBCL, who received rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP)-based chemotherapy, and follow-up at our institution. Here, CD5 is linked to diffuse large B-cell lymphoma.