On the other hand, the levels of IL-17A in tears correlated well with OSDI score (R = 0.60, P<0.001; Fig 3A), Schirmer I test (R = -0.81, P<0.001; Fig 3B), BUT (R = -0.82, P<0.001, Fig 3C) and CFS score (R = 0.83, P<0.001; Fig 3D).The IL-17A mRNA expression in conjunctiva correlated well with OSDI score (R = 0.64, P<0.001; Fig 4A), Schirmer I test (R = -0.83, P<0.001; Fig 4B), BUT (R = -0.85, P<0.001; Fig 4C) and CFS score (R = 0.85, P<0.001; Fig 4D). This evidence concerns the gene IL17A and myalgic encephalomeyelitis/chronic fatigue syndrome.