MYC and Burkitt lymphoma: In BL, the translocation of c-MYC onto the immunoglobulin heavy chain gene locus at 14q32 is the most common, occurring in approximately 80% cases, while variant translocations of c-MYC with the immunoglobulin kappa or lambda light chain genes at 2p12 or 22q11, respectively, occur in approximately 10% of cases.