The HWLs to thermal and mechanical stimulations increased significantly after intra-ACC injection of 0.5 nmol of galanin (Hot-plate Test: Fleft/left = 162.50, P < 0.001; Fright/right = 286.00, P < 0.001; Randall Selitto Test: Fleft/left = 85.52, P < 0.001; Fright/right = 161.90, P < 0.001), or 1 nmol of galanin (Hot-plate Test: Fleft/left = 410.80, P < 0.001; Fright/right = 292.60, P < 0.001; Randall Selitto Test: Fleft/left = 176.30, P < 0.001; Fright/right = 226.40, P < 0.001) compared with the control group in rats with mononeuropathy. The gene discussed is GAL; the disease is mononeuropathy.