Another group of rats with mononeuropathy (n = 8) received intra-ACC injection of 1 μl of 0.9% saline, followed 5 min later by intra-ACC injection of 1 nmol of M871, there were no marked influences on the HWLs to thermal and mechanical stimulation after intra-ACC administration of the selective galanin receptor 2 antagonist M871 in rats with mononeuropathy, as shown in Fig. 4. This evidence concerns the gene GALR2 and mononeuropathy.