MBNL1 and myotonic dystrophy type 1: Apart from hairpin structures, it is also known that CAG repeats in polyQ diseases, similar to CUG repeats in DM1, can form ribonuclear foci that colocalize with RNA-binding proteins such as muscleblind-like 1 (MBNL1), and cause misregulation in alternative splicing (Ho et al., 2004, 2005; Yuan et al., 2007; Hsu et al., 2011; Mykowska et al., 2011; Wang et al., 2011).