CXCR3 and age-related macular degeneration: Interestingly, control individuals exhibit an age-related increase in CD4+CXCR3+, which does not occur in patients with AMD – in the exudative AMD group, there is even a small but insignificant trend (ρ = −0.31, p = 0.092) towards lower CD4+CXCR3+ with age.