Moreover, stimulation of the antiviral pattern recognition receptors such as TLR7/8 with IMQ, a synthetic agonist, is sufficient to trigger psoriasis‐like skin inflammation in mice and psoriasis in humans (Wu et al, 2004; Fanti et al, 2006; van der Fits et al, 2009), indicating that the antiviral signaling pathway may be involved in its etiologic mechanism. The gene discussed is TLR7; the disease is psoriasis.