The most important and well-accepted prognostic criteria (metastasis size, number of metastases, preoperative CEA level, disease free interval from the treatment of the primary CRC and the nodal status of primary CRC), as counted both separately and by Fong’s clinical score [4], were equal and exhibited no significant differences (p = 0.08). This evidence concerns the gene CEACAM5 and colorectal carcinoma.