DLG4 and depressive disorder: The NO system has been implicated in the treatment,22, 46, 47, 48, 49, 50, 51, 52, 53, 54 as well as the pathobiology of depression.49, 50, 55, 56, 57 We, therefore, further investigated PSD-95, nNOS, CAPON and sGC-β1.