When compared with C-ME/CFS short-duration cases, A-ME/CFS long-duration cases had significantly reduced levels of CSF IL5 (P=0.001), IL13 (P=0.0001), IL17 A (P=0.0002) and CXCL9 (MIG; P=0.007). This evidence concerns the gene CXCL9 and myalgic encephalomeyelitis/chronic fatigue syndrome.