There are many known mutations in DLBCL, but the most important ones include those affecting the genes involved in epigenetic modifications (such as mutations in acetyltransferases and histone methyltransferase MLL2), as well as those involved in the regulation of proliferation, differentiation, and apoptosis, such as BCL6 and BCL2. Here, BCL6 is linked to diffuse large B-cell lymphoma.