Importantly, macrophages recovered from sepsis-surviving Il1rl1−/− and Stat6−/− mice harboured significantly fewer bacteria than macrophages from sepsis-surviving WT mice (Fig. 5f), showing the key role of ST2 and STAT6 in the impaired bactericidal activity of the macrophage from sepsis-surviving mice. The gene discussed is IL1RL1; the disease is Sepsis.