FZD8 and lobular neoplasia: Urine levels of respective Wnt-3A, FZD-8, and DKK-1 were 71.71 ± 1.31, 5.96 ± 0.20, and 2.07 ± 0.10 ng/mL for healthy individuals; 64.51 ± 1.01, 5.85 ± 0.16, and 2.68 ± 0.11 ng/mL for SLE patients; 64.69 ± 1.73, 6.41 ± 0.21, and 2.87 ± 0.22 ng/mL for LN-SLE patients; and 64.43 ± 1.25, 5.64 ± 0.20, and 2.58 ± 0.13 ng/mL for non-LN patients (Table 3 and Figure 2).