We explored the effect of DG on breast cancer stem-like cells from three breast cancer lines having differential hormone receptor expression, that is MDA-MB-231, (a triple receptor namely, estrogen receptor-ER), progesterone receptor-PR and human epithelial growth factor receptor2-HER2 negative cell line, T47D (PR and HER2 negative, ER positive) and MCF7 (HER2 negative, ER/PR positive), so that the effect of DG in different types of breast cancers could be analyzed. Here, ESR1 is linked to breast cancer.