In overall analysis no publication bias was found in assessment of the relation between serum level (coefficient = 0.9; 95% CI:-1.4-3.2; p = 0.44) and urine level (coefficient = 1.1; 95% CI:-3.9-3.3; p = 0.09) of cystatin C with AKI. The gene discussed is CST3; the disease is acute kidney injury.