In fact, TSLP is now widely considered to underlie some of the most prevalent inflammatory allergic disorders, such as the atopic diseases (asthma, atopic dermatitis and atopic rhinitis), chronic obstructive pulmonary disease (COPD) and eosinophilic esophagitis9, 10, 11, 12, and has been annotated as a genetic risk factor for the development of asthma13, 14, 15 and eosinophilic esophagitis16. The gene discussed is TSLP; the disease is chronic obstructive pulmonary disease.