For instance, tumor necrosis factor alpha (TNF-α), interleukin-1-beta (IL-1β), interleukin-6 (IL-6), and CXCL8 (interleukin-8) levels become rapidly and substantially increased during neonatal sepsis [4, 6, 7, 10, 11]. This evidence concerns the gene IL1B and Neonatal sepsis.