In addition, the culture supernatant ofASCs isolated from breast cancer patients withpathological stage III had an ability to inducedifferent cytokines such as IL-4, TGF-β1 andIL-10 in PBLs and to upregulate CD4+CD25highFoxp3+ T regulatory cells (20). The gene discussed is TGFB1; the disease is breast carcinoma.