Trubiani et al.(78) reported that human periodontal ligamentstem cells (hPDLSCs) seemed to be ideal sourcesfor MS treatment due to their ability to secreteneurotrophic factors and by modulate expressionof TNF-α, IL-1β, IL-10, Nrf2, and Foxp3. The gene discussed is FOXP3; the disease is myeloid sarcoma.