EGFR and neoplasm: The literature is conflicting concerning EGFR and malignancy, as some have found that high expression is positively related to tumor grade (Caltabiano et al., 2013; Diedrich et al., 1995; Halper et al., 1999) whereas others have found the opposite or no differences (Baxter et al., 2014; Guillaudeau et al., 2012; Jones et al., 1990; Kuratsu et al., 1994; Narla et al., 2014; Wernicke et al., 2010).