It has been reported that loganin could protect against pancreatitis by inhibiting NF-κB activation [23] and also protect against hydrogen peroxide-induced apoptosis by inhibiting phosphorylation of JNK, p38, and ERK 1/2 in SH-SY5Y cells, which share similar signaling pathway with cisplatin-induced kidney injury [45]. The gene discussed is MAPK8; the disease is kidney injury.