CD8+ T lymphocytes were closely related with the atherosclerosis of adult patients.8 Similarly, in this study, the OSAHS group had a significantly higher percentage of CD8+ T lymphocytes (P<0.05) and a significantly lower CD4+/CD8+ ratio (P<0.05) than those of the control group, suggesting that children with OSAHS underwent immune function decline. The gene discussed is CD4; the disease is atherosclerosis.