CD8+ T lymphocytes were closely related with the atherosclerosis of adult patients.8 Similarly, in this study, the OSAHS group had a significantly higher percentage of CD8+ T lymphocytes (P<0.05) and a significantly lower CD4+/CD8+ ratio (P<0.05) than those of the control group, suggesting that children with OSAHS underwent immune function decline. This evidence concerns the gene CD8A and obstructive sleep apnea syndrome.