Tam et al. reported that the OSAHS group (n=44, 7.3 years old on average) had significantly higher levels of INF-γ and IL-8 than those of the control group (n=69, 7.6 years old on average), but the two groups had similar IL-2, IL-4, IL-6, IL-8 and TNF-α levels.15 Serum IL-6 level increased but IL-10 level decreased in children with OSAHS, which were recovered to normal after adenoidectomy and tonsillectomy. This evidence concerns the gene TNF and obstructive sleep apnea syndrome.