Oxidative stress and oxidative damage play a significant role in several ocular diseases including the age-related macular degeneration, cataract, uveitis, corneal inflammation, keratitis, etc.(16) The toxic effects of reactive oxygen species and other free radicals can be eliminated by specific antioxidant enzymes (SOD, GPx, CAT, etc.)which can help the cell to regain the pro-oxidant-antioxidant balance. Here, SOD1 is linked to age-related macular degeneration.