HCRT and Cataplexy: Here, we found that definite cataplexy, the pathognomonic symptom of narcolepsy, may occurin the absence of CSF HCRT-1 deficiency (patients 1, 2, 4, and 6), even in the context ofthe HLA DQB1*06:02 genotype and when narcolepsy is not secondary to another medicalcondition.