CSF hypocretin-1(n = 6) and histamine/tele-methylhistamine (n = 5)levels were assessed twice (median interval: 14.4 months) in four patients with definiteand in two with atypical cataplexy and hypocretin level greater than 100 pg/mL atbaseline. The gene discussed is HCRT; the disease is Cataplexy.