PAGE4 and posterior cortical atrophy: Of the 22 CTAs selected initially by Shiraishi et al. [49], Takahashi et al. [51] found that, in mRNA samples extracted from surgical samples, at least 5 CTAs (CEP55, NUF2, TTK, PBK, and PAGE4) appeared to be differentially expressed between metastatic and localized PCa both by quantitative PCR and the nanowire technology.