Moreover, immunohistological analysis of the protein levels of USP9X and CEP131 using human tissue arrays that included breast carcinoma samples and normal mammary tissues showed that both USP9X and CEP131 were highly expressed in breast carcinoma samples (Fig. 6d, upper panel), and the levels of their expression were strongly correlated with each other (Fig. 6d, lower panel) and with the progression of breast cancer (Fig. 6d, upper panel). Here, CEP131 is linked to breast cancer.