Interestingly, proteomics analysis and molecular study suggest that CEP131 is a ubiquitinated protein14, 15, and, significantly, CEP131 has been reported to play an important role in the maintenance of the genome stability at the time of cell cycle progression13, suggesting that CEP131 is required for proper centrosome duplication and hinting a potential role for this protein in cancer development and progression. The gene discussed is CEP131; the disease is cancer.