Although we observed a better correlation between PCM1 and USP9X than that between CEP131 and USP9X in breast cancer samples, the effect of USP9X depletion on the expression of PCM1 was not as dramatic as that of CEP131, suggesting that PCM1 is a potential, but not major, substrate of USP9X in centrosome. This evidence concerns the gene CEP131 and breast carcinoma.