MTOR and glomerular disorder: The findings of three different studies revealed that the mechanistic target of rapamycin (mTOR) signaling plays an important role in the physiology and phenotype of PECs and that changes in mTOR activity can trigger PEC activation or necrosis in experimental glomerular disease (Kurayama et al. 2011; Hamatani et al. 2014; McNicholas et al. 2016).