This observation is consistent with two studies showing that after 8 h of infection with S. aureus, C. elegans modified the production of defense genes (clec-71, sodh-11, cyp-37B1, lys-5) that have xenobiotic detoxification potential or antimicrobial activities, and then protect host by participating to host response (Irazoqui et al., 2010; Visvikis et al., 2014). The gene discussed is AASDHPPT; the disease is infection.