In addition, there are already several genome-wide methylation studies in the offspring of GDM mothers [32–36], which have led to the identification of functional networks (various metabolic disease pathways and processes, cell growth and death regulation, endocytosis, inflammatory response, MAPK signaling, MODY, NOTCH signaling, type 2 diabetes) which are epigenetically programmed through GDM exposure. Here, HNF4A is linked to gestational diabetes.