Collectively, these findings, although suggestive of a possible influence of AML cells on NK cell development, are still incomplete, as BM and PB NK cell subsets from the same patient have not been examined, and the possibility that the observed phenotype is due to a preferential migration of more mature CD56low/KIR+/CD57+ NK cells from BM to PB is still open (56). Here, KIR3DL1 is linked to acute myeloid leukemia.