Collectively, these findings, although suggestive of a possible influence of AML cells on NK cell development, are still incomplete, as BM and PB NK cell subsets from the same patient have not been examined, and the possibility that the observed phenotype is due to a preferential migration of more mature CD56low/KIR+/CD57+ NK cells from BM to PB is still open (56). The gene discussed is B3GAT1; the disease is acute myeloid leukemia.