CXCR3 and neoplasm: Indeed, unlike circulating CD56highCD16− but similar to dNK cells, CD56highCD16− TINK cells express high levels of CD9, CXCR3, produce VEGF, and have a lower cytotoxic potential, suggesting that similar maturation/polarization mechanisms occur in the decidua and tumor microenvironment of PB NK cells (47–49).