For example, exosomes may express Fas-L (11) or galectin (12), which are responsible for the induction of apoptosis in activated T-lymphocytes, the inhibition of DCs maturation (13), the impairment of the lymphocyte response to IL-2 (14), the downregulation of the cytolytic activity of NK-cells (15), the generation of regulatory T-cells (16), and the blockage of the binding of tumor-specific antibodies to tumor cells to reduce antibody-dependent cell cytotoxicity reactions (17). The gene discussed is IL2; the disease is neoplasm.