It has been specifically suggested that nNOS-NOS1AP interaction could be a therapeutic target in schizophrenia (Weber et al., 2014; Freudenberg et al., 2015), while NOS1AP has emerged as a highly significant associated gene in cardiovascular conditions (Arking et al., 2006; Kapoor et al., 2014). The gene discussed is NOS1AP; the disease is schizophrenia.