BRD4 and laryngotracheoesophageal cleft: To understand whether the properties of BRD4 binding to clinically relevant genetic risk loci is confined to PC and BC only, or such selectivity can also be observed to other diseases and traits, we retrieved binding information for BRD4, MED1 and H3K27Ac profiles available for the lynphoblastoid cell line H2171 derived from a metastatic site in a LC patient [10] and from the malignant peripheral nerve sheath tumor Schwann cells 90-8TL [36] (Additional files 12, 13, 14, 15, 16, 17 and 18).