IRF7 and cancer: As discussed above (section B: The AZA immune gene set (AIM)), cancer samples from the TCGA (melanoma, ovarian, colorectal, breast and lung) could be clustered into high and low immune groups according to the levels of AZA-induced expression of IFN viral defense genes (IRF7, IFI27, RIG-1, IFI44, IFI44L, IFI16, STAT1, IFNB1, DDX41, MX1, OASL, TMEM173, MB21D1, IFI6) [91, 92].