Thus, reduced migration and invasion ability of HCC cells (SNU449) when co-cultured with premiR-199a-3p-transfected HSCs (LX2) revealed that miR-199a-3p could diminish both HGF and cMET and thus abrogate the generation of signal in HSCs and its transmission into CACs. The gene discussed is MET; the disease is hepatocellular carcinoma.